【摘要】 变异黄芪经甲醇热回流提取,浸膏用稀盐酸溶解,氯仿萃取除杂质,然后用氢氧化钠调pH值至9～11,依次用氯仿、乙酸乙酯、正丁醇萃取。正丁醇萃取物经硅胶柱层析进行分离、纯化,得到一种白色针状晶体25.3mg。通过熔点和IR、MS、1HNMR、13CNMR等鉴定其化学结构,确定为苦马豆素。更多还原

【Abstract】 The residue was extracted by hot methanol from A.variabilis Bunge powder,acidified with thin HCl and filtrated to give acid liquid.The acid liquid was extracted with CHCl₃ to remove impurity.Then,its pH was adjusted to 9-11 with NaOH to give basic liquid.The basic liquid was extracted with CHCl₃,ethyl actate and n-butanol successively ,and recovered the solvents.The constituents in n-butanol part were isolated on silica gel column chromatography,and obtained a white crystal （25.3 mg）.The chemical structures were identified as swainsonine by means of MP and IR,MS,¹HNMR,¹³CNMR.更多还原