【摘要】 目的　了解病毒性肝炎合并输血传播肝炎病毒 (TTV)感染对肝功能及其预后的影响。方法　采用微板核酸杂交技术检测了 92例各型病毒性肝炎患者血清中的TTVDNA ,并对检测结果和临床资料进行统计学分析。结果　 92例各型慢性病毒性肝炎患者中TTVDNA阳性 15例 ,阳性率 16 .3%。其中乙型肝炎 10例 ( 6 6 .6 7% ) ,丙型肝炎 2例 ( 13.33% ) ,戊型肝炎 1例 ( 6 .6 % ) ,原因不明的肝炎 2例 ( 1.33% )。 92例患者临床分型中慢性肝炎中度 2 3例 ,阳性 3例 ( 13.0 4 % ) ;慢性肝炎重度 2 7例 ,阳性 4例 ( 14 .81% ) ;肝炎肝硬化 4 2例 ,阳性 8例( 19.0 5 % )。各型间无统计学差异。在慢性肝炎、肝炎肝硬化中TTVDNA阳性与TTVDNA阴性患者的肝功能无统计学差异。结论　病毒性肝炎合并TTV感染不影响肝功能及病情预后。更多还原

【Abstract】 Objective To explore effect on liver function of viral hepatitis after infected with transfusion transmitted virus (TTV). Methods 92 cases of viral hepatitis infected with TTV were detected. TTV?DNA in blood serum of various viral hepatitis were detected. Results After detected, data and clinical information of these patients were analyzed statistically. The results showed that, in the 92 cases, the TTV?DNA positive rate of various chronic viral hepatitis was 16.3%(15 cases), among them, hepatitis B was 66.67%(10 cases), hepatitis C was 13.33%(2 cases), hepatitis E was 6.6%(1 cases), non A to G hepatitis was 13.33%(2 cases). With regard to the clinical type, the rate of middling chronic hepatitis was 13.04% (3 cases) , the rate of heavy chronic hepatitis was 14.81% (4 cases), the rate of hepatitis with liver cirrhosis was 19.05% (8 cases). There was no significant difference among the typings, or among liver function between the TTV positive of the chronic hepatitis, hepatitis with liver cirrhosis and TTVDNA negative. Conclusion It is indicated that viral hepatitis infected with TTV does not affect liver function and prognosis.更多还原