【摘要】 利用转基因植物生产亚单位疫苗用于口服主动免疫具有安全、廉价和方便等优点。植物可以正确地表达细菌和病毒抗原基因 ,对动物及人类的临床实验研究表明 :食用表达某种抗原的转基因植物可在实验动物或人群体内激起系统免疫和粘膜免疫 ,产生相应的特异性抗体 ,这些结果表明了植物口服疫苗的可行性。此外 ,在治疗自身免疫疾病以及癌症等方面 ,植物口服疫苗也具有值得关注的作用更多还原

【Abstract】 The vaccine production systems using edible plant are safer, less expensive and more convenient for delivery than those derived from mammalian cells or microorganisms. Plants can faithfully express the bacterial or viral antigen s. Recent studies have shown that the vaccinogens expressed in plant can induce both the systematic and mucosal responses of animals and humans. Moreover, the potential of edible plant-drived vaccines in treatment for cancers and auto-i mmune diseases is discussed.更多还原