【摘要】 在研究链霉菌Streptomycessp SC1 2 0抗荔枝霜疫霉菌活性代谢产物的过程中 ,分离得到一对人鼻咽癌细胞具有细胞毒作用的抗生素。通过UV、IR、HR MS、 1H NMR、13C NMR、DEPT、1H 1HCOSY、HMQC、HMBC等波谱分析 ,鉴定其结构与Pimprinine相同。首次报道Pimprinine对人鼻咽癌细胞具有细胞毒作用更多还原

【Abstract】 During the course of the investigation of the antifungal metabolites against Peronophythora litchii from the fermentation broth of Streptomyces sp SC120, an antibiotics that exhibited the cytotoxicity to CNE 2 was isolated By spectral (UV, IR, HRMS, 1H NMR, 13 C NMR, 1H 1H COSY, HMQC and HMBC) analyses, its structure was identified as pimprinine The cytotoxicity of pimprinine to CNE 2 was reported for the first time更多还原