Objective To observe the effect of lidocaine on acute lung injury induced by oleic acid. Methods 36 rabbits were randomly divided into three groups : normal control group,oleic acid group, lidocaine and oleic acid group. Malondialdehyde(MDA) content in rabbit's serum and MDA,protein content in broncho-alvedar lavage fluid(BALF) were detected respectively. Results Compared with oleic acid group,the MDA content in rabbit' s serum and in BALF, protein content in BALF and wet-to-dry weight ratio of the lung in ...