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利用空间分辨漫反射无损测量生物组织的光学参量

Noninvasive measurement of spatially resolved diffuse reflection for optical parameters of biological tissue

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【作者】 许棠张春平王新宇张连顺祁胜文田建国

【Author】 XU Tang ZHANG Chun-ping WANG Xin-yu ZHANG Lian-shun QI Sheng-wen TIAN Jian-guo (Photonics Center, Institute of Physics, Nankai University, Tianjin, 300071)

【机构】 南开大学物理科学学院光子学中心南开大学物理科学学院光子学中心 天津300071天津300071天津300071

【摘要】 利用空间分辨漫反射光确定生物组织的光学参量进行了实验研究 ,分别用光纤探测器和 CCD无损测量了半无限大生物组织 (牛脂肪和牛肉 )表面的漫反射光的径向分布 .由漫射方程对漫反射光强的相对分布值作非线性拟合确定了生物组织的吸收系数和约化散射系数 ,所得结果与国外报道的绝对测量法测量的结果相比 ,其差别小于 9.4 % .研究结果表明 ,光纤测量和 CCD测量有较好的一致性 ,而 CCD探测具有测量准确、简单和快捷的特点 .

【Abstract】 The measurement of spatially resolved diffuse reflection for determining the optical parameters of biological tissues is investigated experimentally. The radial distribution of diffuse reflection light at 633nm from the bovine fat and bovine muscle is measured by using a optic fiber detector and CCD respectively. The absorption and reduced scattering coefficients of bovine tissues are derived by nonlinear fitting of diffusion equation with the relative distribution data of diffuse reflection light intensity. The results are compared with the published data derived from absolute measurements, and the differences between the results and the published data are less than 9.4%. The investigation shows that the data measured by optic fiber detector is in good agreement with that by CCD, the method of using CCD is shortcut and has better precision.

【基金】 国家自然科学基金资助项目 (No.6 0 0 780 12 ,No.6 0 0 2 5 5 12 )
  • 【文献出处】 物理实验 ,Physics Experimentation , 编辑部邮箱 ,2003年11期
  • 【分类号】Q632
  • 【被引频次】1
  • 【下载频次】147
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