【摘要】 目的:研究脐血瘦素水平与新生儿性别、孕周、出生体重、身高、体重指数及胎盘重量的关系。方法:应用酶联免疫法（ELISA）测定脐血瘦素水平,共测定了46份样本,运用统计学方法分析其与新生儿性别、孕周、出生体重、身高、体重指数BMI(即体重除以身高的平方,单位为kg·m^-2及与胎盘重量等的关系。结果:脐血瘦素水平与出生体重、身高、体重指数及胎盘的重量有着显著性相关,而男女性别间脐血瘦素水平无显著性差异。结论:脐血瘦素水平与新生儿孕周、出生体重、身高、体重指数及胎盘重量有密切关系,临床测定脐血瘦素水平对预测胎儿出生体重和生长发育有重要意义。更多还原

【Abstract】 To investigate the rcletionship between the concentration of leptin with the sex, fetal weight, fetal height, fetal body mass index, gestational age and placental weight. Methods: Leptin concentrations in the serums of cord blood in 46 newborns(male=29, femal = 17, gestational age 31-41 weeks, birth weigh 1.6-3.8 kg, birth height 35-52 cm) were measured by ELISA. The results were analyzed using SAS statistic software. Results: Leptin concentrations in the serums of cord blood were positively correlated with birth weight ( r =0.463, P<0.01), birth height (r= 0.358, P<0.05),body mass index (r = 0.328, P< 0.05) ,gestational weeks( r = 0.49, P<0.01) and placental weight(r = 0.363, P<0.05). Serum leptin levels of male neonates(7.43±10.03ng/mL) were not significantly different from those of female neonate(8.87±13.15 ng/mL) . Conclusion: There is significant relationship between the cord serum leptin and the fetal growth. They will be used as a meaningful parameter in evaluating fetal growth practically.更多还原