【摘要】 目的　清醒镇静在贲门失弛缓症球囊扩张治疗中的镇静效果及安全性。方法　选 60例贲门失弛缓症患者 ,随机分为对照组 (2 0例 )和实验组 (4 0例 ) ,对照组术前肌注安定 10mg、度冷丁 10 0mg ,实验组应用清醒镇静剂咪唑安定缓慢静注 ,总量为0 0 5mg/kg ,其后行球囊扩张术。术前、术中和术后分阶段记录患者生理指标及耐受程度。结果　与对照组相比 ,清醒镇静剂组患者镇静程度适中 ,耐受性提高 ,心血管及呼吸功能参数均佳 ,差异具显著性 (P <0 0 5 )。结论　清醒镇静在内镜治疗贲门失弛缓症中具有疗效可靠、操作简易、便于监测、依从性提高等特点。更多还原

【Abstract】 Objective To evaluate the efficiency and safety of application of conscion of conscious sedation on endoscopic balloon dilatation for achalasia of cardia.Methods Sixty patients with achalasia of cardia were randomly divided into two groups,namely the contrast group (20 cases) and the disposal group (40 cases).The patients of the contrast group received diazepam 10 mg i.m. and meperidine 100 mg i.m.,while the patients of disposal group received conscious sedation agent midazolam i.v.(total dose 0 02 mg/kg) before treatment.The physiological index and the sense degree of the patients were monitored during preoperative,in operative and postoperative phases.Results The patients receiving midazolam showed better tolerance,and the cardiovascular and respiratory function parameters in patients with disposal group excelled those of the controls.Conclusions Conscious sedation is safe and effective in endoscopic balloon dilation for achalasia of cardia.更多还原