【摘要】 目的　通过采用乌司他丁与生大黄联合治疗急性胰腺炎大鼠动物模型 ,寻找治疗急性胰腺炎更好的治疗方法。方法先建立急性胰腺炎大鼠模型 ,然后分为四组 ,分别测定每组血清液粉酶 (AMS)肿瘤坏死因子 (TNFα)及胰腺标本染色及大概生存时间。结果　A、B、C、D组TNFα、AMS含量及胰腺病理改变呈A >B >C >D ,而生存时间显著不同。结论　乌司他丁、大黄联合治疗急性坏死性胰腺炎大鼠效果比单一效果更佳更多还原

【Abstract】 Objective Study rhubarb and ulinastitin combinatively used to treat the acute necrotizing pancreatitis of rats.Seek for a more effective treatmnet.Methods 80 rats were randomly divided into four groups,acute necrotizing pancreatitis animal models set up and measured the amylase(AMS),toumor necrosis factors(TNF α) of rats blood samples.Results AMS?TNF α of rats blood samples and pathological change ranged as:group A>group B>group C>group D( P <0 05),Survival times,which of group A,B and C compared with that of group D,were definitely diffential( P <0 05) Conclusions Ulnastatin in combination with rhubarb are more effective than either of them in the treatment of acute necrotizing pancreatitis of rats.更多还原