【摘要】 本试验研究了药用真菌 980 0金耳菌丝发酵产物对小白鼠血栓形成的影响和对大鼠脑脂质过氧化物等指标的影响。结果表明 ,0 .8g/kg·d剂量的金耳菌丝发酵产物能明显对抗小鼠体内血栓的形成 ,高剂量组对脑组织缺血其过氧化脂质的分解产物丙二醛含量明显增多有显著的抑制作用 ,能明显抑制ADP诱导的血小板聚集 ,对动物凝血酶原的作用时间有延长作用 ,给药 5分钟后能明显增加动物脑膜血流量。本实验结果表明该产物对动物血栓形成有较好的抑制作用。更多还原

【Abstract】 After the fermented products of mycelium from Tremella aurantialba 9800 0.8 g/kg.d were given to thrombusis mice,the anti-thrombus effect was prominently efficient in comparison with the control.The group of the high dose could significantly inhibit the peroxide lipid from decomposing into MDA in brain tissue of ischemia state,as well as the platelet aggregation that induced by ADP in normal rats.The fermented products could remarkablely prolong the clotting time of the thrombogen and increase the volume of meninges′ blood flow after given the products(in vitro) in 5min.The conclusion is that the fermented products of mycelium from Tremella aurantialba 9800 have distinct biological activeness on anti-thrombus.更多还原