【摘要】 目的 :了解天津地区鲍曼不动杆菌的耐药情况 ,以助于临床合理用药。方法 :收集临床分离的不动杆菌 ,培养鉴定。采用纸片扩散法 (K_B法 )或微量稀释法 (MIC)测定18种抗菌药物的敏感情况 ,用WHONET5软件分析结果。结果 :天津市8家三级甲等医院2001年度共收集390株不动杆菌 ,其中下呼吸道感染不动杆菌分离率高 ,为88 2 % ,以鲍曼不动杆菌为主。鲍曼不动杆菌对亚胺培南耐药率最低 (7 8 % ) ,其次是头孢哌酮/舒巴坦(11 6 % )、氧氟沙星 (13 9 % )及阿米卡星 (14 8 % )。头孢唑啉的耐药率最高 (95 1% )。结论 :鲍曼不动杆菌在呼吸道标本中分离率高 ,易引起院内感染 ,耐药率高 ,应注意对该菌的防治更多还原

【Abstract】 Objective:To study the drug resistance of Acinetobacter baumannii in Tianjin for clinical drug use.Methods:The collection of clinical isolated strains of Acinetobacter spp.and culture and identification were completed.The bacterial susceptibility to18antimicrobial agents was determined by Kirby_Bauer or micro diluˉtion methods.The results were analyzed with Whonet5software.Results:Three hundred and ninety strains were collected from eight hospitals in2001.Isolate rate of lower respiratory tract was88.2%,and A.baumannii was major.The rate of resistance to imipenem for A.baumannii was7.8%,followed by cefoperazone/sulbactam(11.6%),ofloxacin(13.9%),and amikacin(14.8%).The rate of resistance to cefazolin was95.1%.Conclusion:A.baumannii is highly isolated from lower respiratory tract and easily resulted in nosocomial infection.Attention should be paid for controlling and prevention.更多还原