【摘要】 目的 :了解悬雍垂、软腭各组织成分的分布规律 ,探讨各组织成分量的变化与阻塞性睡眠呼吸暂停综合征(Obstructivesleepapneasyndrome,OSAS)临床分度间的关系。方法 :对112例OSAS手术治疗所切除的悬雍垂及部分软腭标本进行组织学定量观察 ,对其基本组织成分 :腺体、骨骼肌、脂肪及纤维血管间质所占比例进行统计学分析。结果 :悬雍垂、软腭的主要构成成分为腺体和纤维血管间质 ,脂肪含量少 ;骨骼肌成分悬雍垂、软腭略有不同 ,前者稍高于后者 ,但悬雍垂、软腭的腺体、纤维血管间质、脂肪及骨骼肌4种成分的含量在OSAS临床轻、中、重度的各组间均无显著性差异(P>0.05)。结论 :悬壅垂、软腭的脂肪沉积和骨骼肌量的多少对OSAS发病的轻重并不起重要作用更多还原

【Abstract】 Objective:To investigate the distributed regulation of tissue in uvula and palate,and the relaˉtionship between the clinical degree of obstructive sleep apnea syndrome(OSAS)and changes of tissue compoˉnents.Methods:To observe the histological quantitative changes of the specimens in112palatopharyngealplasty(PPP)with OSAS,and analyze the variance.Results:The gland and the fibrovascular stroma were main compoˉnents of the uvula and palate with less fat.There were more muscle components in uvula than that in palate.There was no significant difference in the changes of four components between clinical degrees of slight,moderate,and severe groups(P>0.05).Conclusion:The deposition of fat and the amount of muscle in uvula and palate have not important role in snoring degress of OSAS.更多还原