【摘要】 目的 :用糖类及其衍生物修饰阿司匹林化学结构 ,合成乙酰水杨酸衍生物。方法 :用乙酰基保护的溴代糖与水杨酸在TEBAC存在下反应 ,合成糖基水杨酸酯。结果 :实验合成了4个糖基水杨酸酯。结论 :测定了其红外光谱、核磁等光谱数据 ,证实其结构更多还原

【Abstract】 Objective:The derivatives of acetosalicylic acid(aspirin)were synthesized by usˉing carbohydrate complexes to modify the structure of aspirin.Methods:Bromo-carbohydrate complexes protected by acetyl and salicylic acid reacted in T EBAC solution.Results:Bromo-carbohydrate complexes protected.Conclusion:Four saccharic salicylic acid were synthesized and their structures were confirmed by their optical spectrum date.更多还原