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氨苄西林细菌内毒素检查的研究

Study of Bacterial Endotoxin Test of Ampicillin

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【作者】 纪丽曼李红胡卫平李静

【Author】 Ji Liman, Li Hong, Hu Weiping, Li Jing (Quality Control Department, North China Pharmaceutical Group Corporation,Shijiazhuang 050015)

【机构】 华北制药集团公司华北制药集团公司 石家庄050015石家庄050015石家庄050015

【摘要】 目的 :建立氨苄西林细菌内毒素检查方法。方法 :按 2 0 0 0年版《中国药典》附录细菌内毒素检查法操作。结果 :氨苄西林在浓度 3.33mg/ ml时对鲎试剂与内毒素反应无干扰因素影响。结论 :细菌内毒素检查法适用于检测氨苄西林中的内毒素。

【Abstract】 Objective: To establish a method for testing the bacterial endotoxin of Ampicillin. Methods: According to appendixⅨ E in CP 2000 the Bacterial Endotoxin of Ampicillin was tested. Results: Neither inhibition nor enhancement was found after the sample was diluted to 3.33 mg/ml. Conclusion: These results suggest that the TAL method is suitable for the detection of endotoxin in Ampicillin.

  • 【分类号】R927.12
  • 【下载频次】15
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