【摘要】 合成了3种具有苯并咪唑基的配体(N3,NTB,EDTB)及其与金属镍的配合物,由此模拟镍超氧化物歧化酶(Ni-SOD)的活性中心结构,对所合成的模拟化合物进行了元素分析和红外、紫外光谱的结构表征,并利用改进的邻苯三酚自氧化法测定了模拟化合物的生物活性.更多还原

【Abstract】 In order to simulate the active site of nickelcontaining superoxide dismutase, three benzimidazolcontaining ligands N,Nbis(benzimidazol2ylmethyl) amine(N3),N,N,Ntri(benzimidazol2ylmethyl) amine(NTB), N,N,N`,N`tetrakis(benzimidazol2ylmethyl)1,2ethanediamine(EDTB) and their complexes with nickel ion were synthesized. The complexes were characterized by elemental analysis, IR and UV spectrums, and their biological activities were determined by means of improved pyrogallol autoxidation.更多还原