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黄龙汤对动物肠运动的影响

Effect of Huanglongtang on Intestinal Motility in Animals

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【作者】 李祥华王文英马凤英李虹

【Author】 LI Xiang hua 1,WANG Wen ying 1, MA Feng ying 1, LI Hong 2 (1.Hubei Medical Staff College,Jingzhou 434000, China; 2.Gongan County Medical School,Douhudi 434300, China)

【机构】 湖北省卫生职工医学院湖北省公安县卫生学校 湖北荆州434000湖北荆州434000434300

【摘要】 目的 :探讨黄龙汤对实验动物肠运动的作用。方法 :采用肠管运动在体实验法测定排便时间及频度和肠推进运动 ,肠管运动的离体实验法测定动物不同肠段运动情况。结果 :黄龙汤能使动物排便时间增快 ,次数增加 ,便稀且不成形。能明显促进动物在体肠推进运动。能增加动物离体回肠蠕动作用 ,对离体十二指肠及结肠则显示明显的抑制作用 ,且这种作用能被Ach短暂拮抗。结论 :黄龙汤对实验动物有明显的泻下作用。可能是由于黄龙汤有促进动物肠肌运动的结果。对十二指肠及结肠显示的这种抑制作用表明本方在致泻的同时 ,可能有解痉止痛作用

【Abstract】 Objective:To investigate the effect of Huanglongtang on intestinal motility of experimental animals.Methods:The way of intact intestinal motility was used to measure time to start defecation and frequency of defecation and intestines moved forward.Isolated intestinal kinesis was used to measure duodenrm,ileum and colon kinesis in animals.Results:Defecation time was moved up and the frequency increased,and it did not take shape.Huanglongtang promoted strikingly intact intestines and isolated ileum motility in animals.There was inhibition to duodenum and colon in vitro in animals by taking Huanglongtang.The inhibition could be antagonized transiently by Ach.Conclusion:Huanglongtang has an outstanding purgative action in animals,which could be as a result of enhancement intestinal motility.The inhibition on isolated dudenum and colon showes that Huanglongtang has an antispasmodic effect while it purges.

【关键词】 黄龙汤十二指肠回肠结肠
【Key words】 HuanglongtangDuodenumIleumColon
  • 【文献出处】 时珍国医国药 ,LiShiZhen Medicine and Materia Medica Research , 编辑部邮箱 ,2003年06期
  • 【分类号】R285.5
  • 【被引频次】5
  • 【下载频次】127
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