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滇黄芩化学成分的分离与鉴定
Isolation and identification of the chemical constituents of roots of Scutellaria amoena C.H.Wright
【摘要】 目的研究滇黄芩 (ScutellariaamoenaC .H .Wright)化学成分。 方法利用各种色谱技术进行分离纯化 ,根据理化性质和光谱数据进行结构鉴定。结果分离得到 8个化合物 ,分别鉴定为 :5 ,7 二羟基 6 甲氧基二氢黄酮 (dihydrooroxylinA ,Ⅰ )、5 ,7,4′ 三羟基 8 甲氧基黄酮 ( 5 ,7,4′ trihydroxy 8 methoxyflavone ,Ⅱ )、千层纸素A(oroxylinA ,Ⅲ )、汉黄芩素 (wogonin ,Ⅳ )、白杨素 (chrysin ,Ⅴ )、黄芩素 (baicalein ,Ⅵ )、去甲汉黄芩素 (norwogonine ,Ⅶ )、( 2S) 5 ,7,2′ ,6′ 四羟基二氢黄酮 [( 2S) 5 ,7,2′ ,6′ tetrahydroxyflavanone ,Ⅷ ]。 结论化合物Ⅰ、Ⅱ为该植物中首次分得
【Abstract】 Objective To study the chemical composition of roots of Scutellaria amoena C.H.Wright.Methods Various chromatographic techniques were used to separate and purify the constituents.Their structures were determined by chemical evidences and spectral analysis.Results Eight compounds were isolated and purified,their structures were identified as dihydrooroxylin A(Ⅰ),5,7,4′ trihydroxy 8 methoxyflavone(Ⅱ),oroxylin A(Ⅲ),wogonine(Ⅳ),chrysin(Ⅴ),baicalein(Ⅵ),norwogonine(Ⅶ),(2 S ) 5,7,2′,6′ tetrahydroxyflavanone(Ⅷ).Conclusion CompoundⅠandⅡare separated from Scutellaria amoena C.H.Wright for the first time.
【Key words】 Scutellaria amoenaC.H.Wright; chemical constituents; dihydrooroxylin A; 5,7,4′trihydroxy 8 methoxyflavone;
- 【文献出处】 沈阳药科大学学报 ,Journal of Shenyang Pharmaceutical University , 编辑部邮箱 ,2003年03期
- 【分类号】R284
- 【被引频次】107
- 【下载频次】1204