【摘要】 目的　观察冠心病患者活化血小板的水平并了解其在不同类型冠心病中的意义。　 方法　选择稳定型心绞痛、不稳定型心绞痛及正常者各 2 0例。应用流式细胞技术 (CD62p)测定其活化血小板水平。其中有 2 2例行冠状动脉 (简称冠脉 )造影检查。　 结果 　冠心病不稳定型心绞痛CD62p水平为 (2 1 72± 7 5 ) % ,较稳定型心绞痛 (10 2 2± 5 2 ) %明显升高 ,且较正常组 (5 82± 2 5 ) %高 ,3者比较有统计学显著差异 (前 2者比较P <0 0 1,后 2者比较P <0 0 5 )。且冠脉病变越重 ,CD62p水平越高。　 结论 　冠心病患者尤其是不稳定型心绞痛患者CD62p水平增高 ,对病情判断及治疗提供依据更多还原

【Abstract】 Objective To observe the level of activated platelet in patients with coronary heart disease(CHD) and to investigate its significance among varieties of CHD. Methods We used 40 patients with CHD and 20 normal subjects.There were 20 patients with stable angina pectoris (SAP) and 20 with unstable angina pectoris(UAP).Flow Cell Monitor(FCM) was used to measure the level of activated platelet.22 cases underwent coronary artery angiography. Results The level of activated platelet was higher in UAP(21 72±7 5)% than that in SAP(10 22±5 2)% and was higher than that in normal subjects(5 82±2 5)% Significant difference was found among three groups( P <0 01 between the first two; P <0 05 between the second and third).The level of activated platelet was significantly higher in serious coronary artery disease. Conclusions The level of activated platelet is increased in the patients with CHD,especially with UAP,which helps to assess the serious degree and provide basis for therapy.更多还原