【摘要】 目的　探讨CT和MRI图像融合技术在颅内病变X刀治疗中的应用及其临床价值。方法　 2 5例病变中包括动静脉畸形 5例、海绵状血管瘤 4例、大脑半球胶质瘤术后残留或复发 3例、听神经瘤术后残留 3例、转移瘤 2例、垂体微腺瘤 2例、垂体腺瘤术后残留 2例、颅咽管瘤术后残留 1例、垂体柄肿瘤病变 1例、间脑胶质瘤 1例和中脑披盖肿瘤病变 1例。图像融合前均行颅脑MRI薄层扫描及常规X刀术前CT定位扫描 ,然后将CT和MRI图像资料传输至工作站上进行图像配准和融合。结果　所有病变在融合图像上均能显示清楚 ,2例转移瘤在融合图上显示出更多的病灶。所有融合图像上的软组织结构、颅骨结构及病灶轮廓均重叠一致 ,最大误差均 <1mm。结论　CT和MRI图像融合技术在X刀治疗中的应用 ,确保了CT定位的精确性 ,避免了病变的遗漏 ,必然会提高颅内病变定向放射治疗的效果 ,并明显降低了并发症的发生率更多还原

【Abstract】 Objective To study the application of fusion of CT and MRI images in X-knife treatment for intracranial lesions.Methods Total 25 patients included:3 gliomas,3 acoustic neuroma,2 pituitary adenoma,one craniopharygioma to be remained or recurred postoperatily,2 pituitary micro-adenoma,5 AVM,4 cavernous angioma,3 metastatic tumour,one neoplasm located pituitary stem and midbrain respectively.Before the fusion of CT and MRI images MRI scan and CT scan for location of X-knife were performed respectively,then MR and CT image were transferred to workstation for the fusion of images.Results All lesions were showed clearly on fusional images and more nodules were observed in 3 metastatic tumour.Skull,soft tissue constructures and the profile of lesions were completely overlaped on overlaped images of CT and MR with an error less 1.0 mm.Conclusion CT and MRI images of head can be accurately registered.The images can show the radiologic informations more clearly than conventional CT image.It provides a safe,effective and little harmful method for X-knife treatment of intracranial lesions.更多还原