【摘要】 目的　通过对移植肾彩色多普勒血流显像 (CDFI)的观察 ,与同位素血流动态 (SPEFT)及移植肾活检结果相对照分析 ,评估CDFI对移植肾排异反应的诊断价值。方法　 65例肾移植术后患者行CDFI及肾活检 ,其中 44例行SPECT。急性排斥组 2 6例 ,慢性排斥组 12例 ,急性肾小管坏死 7例 ,环孢素A中毒 2例 ,正常组 18例。对二维成像、彩色血流图、血流频谱、阻力指数 (RI)、搏动指数 (PI)、收缩期与舒张期血流速度比 (S/D)等参数进行回顾性分析。结果　急性排异组的RI值为 0 .77± 0 .0 5 ,慢性排异反应组的RI值为 0 .72± 0 .0 7,均明显高于正常组 (0 .5 7± 0 .0 7) ,显著性分别Ρ <0 .0 0 1和Ρ <0 .0 2 5。结论　CDFI监测移植肾后的排异反应快速 ,准确无创 ,可早期发现病情变化并指导治疗。更多还原

【Abstract】 Objective To evaluate the value of color Doppler flow image(CDFI)in diagnosis of acute renal allograft rejection in early stage,by comparative study on CDFI,single photon emission computer tomography(SPECT)and biopsy.Methods A total of 65 patients were included in this study,including acute rejection in 26 cases,chronic rejection in 12 cases,acute tubular necrosis in 7 cases,toxic reaction of cyclosporine a in 2 cases and normal in 18 cases.They were all subjected to CDFI and biopsy,and 44 were detected by SPECT.We reviewed two-dimension gray scale picture,spectrogram,perfusion index(PI),resistant index(RI),the ratio of blood flowing velocity of systole period and diastole period(S/D) as correlated to the findings of SPECT and biopsy.Results The RI values were 0.77±0.05 and 0.72±0.07 in acute rejection group and chronic rejection group respectively,which were obviously higher than those in normal group(0.57±0.07).Conclusion CDFI is a fast,accurate and non-invasive technique in evaluating renal transplant rejection early.更多还原