节点文献
化学修饰酶在天然药物研究和生物技术中的应用
Chemical Dressing Enzyme:Its Application in Researches on Natural Drugs and Biotechnology
【摘要】 天然药物研究在现代药物开发中占有十分重要的地位 ,化学修饰可降低天然药物中酶蛋白的免疫原性 ,提高对热稳定性 ,延长酶在体内半衰期 ,提高药效 ;同时对生物技术中酶控药物释放系统和药物靶点确认有一定的作用
【Abstract】 Researches on natural drugs play a very important role in the development of modern medicines. Chemical dressing enzyme can reduces the immunogenicity of zymoprotein in natural drugs, improve stability against heat and prolong the half-life period of enzyme inside the body to improve efficacy of drugs. Meanwhile, chemical dressing enzyme has certain effects on the enzyme-controlled drug-releasing system in biotechnology and the confirmation of drug target site.
【关键词】 化学修饰酶;
天然药物研究;
生物技术;
【Key words】 chemical dressing enzyme; researches on natural drugs; biotechnbology;
【Key words】 chemical dressing enzyme; researches on natural drugs; biotechnbology;
- 【文献出处】 陕西中医学院学报 ,Journal of Shaanxi College of Traditional Chinese Medicine , 编辑部邮箱 ,2003年05期
- 【分类号】R341
- 【被引频次】7
- 【下载频次】477