【摘要】 研究了生物降解性聚 L-乳酸 (PL L A)纤维的水解与其表面仿生化低结晶型磷灰石涂层的形成。用扫描电镜及其附带的 X光能谱、X光衍射、X光电子能谱、红外光谱等方法对磷灰石涂层的形貌、化学与结晶结构进行了表征。结果表明 ,用仿生法得到的磷灰石涂层 ,与天然骨无机成份的结构接近 ,为低结晶型磷灰石。PL L A的水解对磷灰石涂层的形成有一定促进作用 ,但对磷灰石涂层的化学与结晶结构没有影响。这种用仿生法形成的低结晶型磷灰石涂层 ,希望可以增加 PL L A纤维作为骨修复材料时的生物活性。更多还原

【Abstract】 Low crystalline apatite coating was formed on the surface of biodegradable poly(L-lactic acid) (PLLA) fibers by a biomimetic process, i.e., by immersing the fibers in a modified simulated body fluid (SBF) at 37℃ and pH 7.3 after hydrolysis of the fibers in water. The apatite was characterized by scanning electron microscopy with energy dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy. Results showed that the fiber hydrolysis could accelerate the apatite formation but had little effect on the chemical and crystalline structure of the apatite. The structure of the apatite coating formed by the biomimetic method was similar to that of apatite in the natural bone. The bone-like low crystalline apatite coating might exhibit enhanced osteoconductivity when the PLLA fibers are applied in bone reconstruction biomaterials.更多还原