【摘要】 为了对局灶性缺血脑损伤的程度进行无创诊断 ,并对损伤区域进行定位 ,用 SD(Sparague- dawley)实验大鼠建立了一个局灶性缺血脑损伤的动物实验模型 ,采得缺血前到缺血 30 m in时的缺血区域与正常区域的 EEG(Electroencephalogram)信号 ,并采用功率谱熵对 EEG信号进行了分析。结果发现局灶性脑缺血导致 EEG信号的功率谱熵发生了明显的变化。缺血侧的 EEG信号的功率谱熵在缺血 15 min时已经明显低于缺血前的正常值 ,在整个缺血过程中缺血侧的 EEG信号的功率谱熵小于正常区域的功率谱熵。这表明 EEG信号的功率谱熵是一种很好的表征脑缺血损伤的参数 ,具有计算简便、有效的优点更多还原

【Abstract】 A model of SD rat focal ischemic cerebral injury is presented for use in noninvasively detecting both the extent and the location of focal ischemic cerebral injury. EEG signals of ischemic region and normal region are recorded from the moment before ischemia to 30 minutes after ischemia. Then the Power Spectral Entropy(PSE) analysis of EEG is performed. Results show that the PSE of EEG signals changes greatly as a result of focal ischemic cerebral injury. The PSE of EEG signal of ischemic region is less than that before ischemia as the ischemia lasts 15 minutes.The PSE of EEG signals of ischemic region is much less than that of normal region. These indicate that the power spectral entropy of EEG signal is a good index of focal ischemic cerebral injury and the method of power spectral entropy analysis is simple and effective.更多还原