【摘要】 目的 :探讨心跳呼吸骤停后心肺脑复苏 (CPCR)时早期行气管插管供氧与生存及预后的关系。方法 :4 8例实施CPCR患者根据行气管插管时间分早期气管插管组 (A组 ,n =2 5 )和非早期气管插管组 (B组 ,n =2 3) ,后者又分为 <5min组 (n =10 )、 5～10min组 (n =7)和 >10min组 (n =6 )。比较各组自主循环恢复 (ROSC)率和存活 2 4h或存活出院率。结果 :A组及B组的ROSC率、 2 4h存活率和出院存活率分别为 76 0 % ,5 6 5 % (P <0 0 5 )、 4 8% ,30 4 % (P <0 0 5 )和 2 0 0 % ,8 6 % (P <0 0 5 )。B组内各组间也存在差异 ,5min内行气管插管组ROSC、 2 4h存活率及出院存活率分别为 70 0 %、 4 0 0 %和 2 0 0 % ,与A组接近 (P >0 0 5 )。但 5～10min和 >10min才行气管插管组ROSC(5 7 1% ,33 3% )、 2 4h存活率 (2 8 6 % ,16 6 % )及出院存活率 (均为 0 )均低于 5min内气管插管组 (P <0 0 5 )。结论 :对于发生在医院内因各种原因导致的心跳呼吸骤停的患者应在行胸外按压的同时尽早行气管插管 ,建立最有效的人工通气 ,可避免脑功能的不可逆性损害 ,从而提高CPCR的成功率更多还原

【Abstract】 Objective:To investigate the correlation between gi ving oxygen with early endotracheal intubation and survi val in patients with cardiac and respiratory arrest.Methods:Forty eight adult patients were assigned to two groups:Early endotracheal intubation group(Group A,n=25) and late endotracheal intubation group(Group B,n=23).Group B was assigned to three group:less than 5 minutes group(n=10) ,5～10 minutes group(n=7) and more than 10 minutes group(n=6).The rates of the return of spontaneous cir culation(ROSC),survival at 24 hours and survival to hospital disch arge were compared among the groups.Results:The rates of ROSC,survival at 24 hou rs and survival to hospital discharge were 76 0%,56 5%(P<0 05),4 8 0%,30 4% (P<0 05)and 20 0%,8 6%(P<0 05),respect iv ely.There were differences in each group of Group B,too.The rates of ROSC,surviv al at 24 hours and survival to hospital discharge were 70 0%,40 0% and 20 0% in less than 5min group,respectively,and higher than10 min utes group and more than 10 minutes group.Conclusion:The early endotracheal intubation can impr ove the rates of success of CPCR in the patients with cardiac and respiratory ar rest in hospital.更多还原