Polysaccharides extracted from Coprinus comutus fermantation liquid have good effect on diabetic rats. We studiedthe effect of polysaccharides on murine peritoneal macrophages.After i. p two kinds of polysacchaides, the results showed thatmurine peritoneal macrophages were stimulate by both.The phagocytoic activity to neutral red is increased with the doseincreasing of the intracellular polysaccharides.The extracellular polysaccharides stimulate activity of phagocytoic to neutral redtoo,but not as strong as...