【摘要】 ①目的　探讨青地汤防治肺癌放疗反应的效果。②方法　 1 56例肺癌病人分为两组 ,青地汤组 84例连续服用青地汤 2 0剂以上 ,对照组 72例未服药。比较两组放疗反应的发生率及 1、2年生存率。③结果　青地汤组放射性气管炎、放射性肺炎、放射性肺纤维化及因严重放疗反应而被迫中断放疗的发生率分别为 36 .9%、7.1 %、2 5 .0 %、1 0 .7% ,对照组分别为 54 .2 %、1 9.4%、45 .8%、2 7.8% ,两组比较差异有显著性 (χ2 =4.670～ 7.459,P均 <0 .0 5)。青地汤组放射性食管炎发生率 ,治疗中抗生素及糖皮质激素的应用率 ,病人的 1、2年生存率分别为57.1 %、41 .7%、2 6 .2 %、37.8%、2 6 .5 % ,对照组分别为 65 .3 %、54 .2 %、40 .3 %、35 .5 %、2 0 .7% ,两组比较差异无显著性 (χ2 =0 .0 65～ 3 .496 ,P均 >0 .0 5)。④结论　青地汤能有效防治肺癌病人的放疗反应更多还原

【Abstract】 Objective\ To investigate the role of Qing Di Tang(QDT), a herbal decoction of traditional Chinese medicine, in the prevention and treatment of complications of radiotherapy for patients with lung cancer. \ Methods\ One hundred and fifty six patients were divided into two groups, QDT group ( n =84) and control group ( n =72). The patients in QDT group were given the decoction, one dose per day, continuously for more than 20 days. For those in control group received no herbal decoction. The radiation complications and one and two year survival rates between the two groups were compared.\ Results\ The rates of acute trachitis, radiation pneumonitis, radiation pulmonary fibrosis and interruption of radiotherapy due to severe reactions in QDT group were 36.9%, 7.1%, 25.0% and 10.7%, respectively, for those in the control group were 54.2%, 19.4%, 45.8% and 27.8%. The differences between the two groups were significant ( χ 2=4.670-7.459, P <0.05). The rates of acute esophagitis, use of antibiotics, cortical hormone, one and two year survival rates in QDT group were 57.1%, 41.7%, 26.2%, 37.8% and 26.5%, respectively, for those in the control group were 65.3%, 54.2%, 40.3%, 35.5% and 20.7%. The difference was not significant( χ 2= 0.065-3.496, P >0.05). \ Conclusion\ QDT can effectively prevent and treat complications cause by radiotherapy in patients with lung cancers.更多还原