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脑外伤后迟发性尿崩症的诊断及治疗

Diagnosis and treatment of delayed diabetes insipidus following brain injury

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【作者】 蒋宇钢车东方张治平张凌云

【Author】 JIANG Yugang,CHE Dongfang,ZHANG Zhiping, ZHANG Lingyun Department of Neurosurgery, Xiangya Second Hospital, Central South University, Changsha 410011, China

【机构】 中南大学湘雅第二医院神经外科中南大学湘雅第二医院神经外科 湖南长沙410011湖南长沙410011湖南长沙410011

【摘要】 目的 探讨脑外伤患者发生迟发性尿崩症的诊断及治疗方法。方法 回顾性分析我科近5年脑外伤后发生迟发性尿崩症的 19例患者。根据临床症状、实验室检查及头颅MRI检查早期明确迟发性尿崩症的诊断并给予及时处理。结果 所有患者的尿量均恢复正常 ,其中 2例需终生服用1 去氨基 8 右旋 精氨酸加压素 (DDAVP)替代治疗。结论 脑外伤后迟发性尿崩症通过临床表现、实验室检查及头颅MRI检查明确诊断 ,行抗利尿激素制剂和口服的抗利尿药物治疗后效果满意。

【Abstract】 Objective To study the diagnosis and therapy of delayed diabetes insipidus following brain injury . Methods Nineteen patients with delayed diabetes insipidus after brain injury who were admitted to our department in recent 5 years were analyzed retrospectively. Based on clinical manifestations, laboratory examinations and MRI, early diagnosis was made and effective therapies were carried out.Results Delayed diabetes insipidus was controlled completely in all cases, among which 2 patients needed to take 1 deamino 8 arginine vasopressin (DDAVP) replacement therapy for the rest life.Conclusion Diagnosis of delayed diabetes insipidus following brain injury can be early made based on clinical manifestations, laboratory examination and MRI. The effects of vasopressin and antidiuretic agents treatment are satisfactory.

【关键词】 脑损伤尿崩症诊断治疗
【Key words】 Brain injuryDiabetes insipidusDiagnosisTherapy
  • 【文献出处】 中华神经外科疾病研究杂志 ,Chinese Journal of Neurosurgical Disease Research , 编辑部邮箱 ,2003年03期
  • 【分类号】R651.15
  • 【被引频次】3
  • 【下载频次】208
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