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持续性植物状态猫脑脊液中多巴胺变化实验研究
Experimental study on the changes of dopamine in cerebrospinal fluid in the cats with persistent vegetative state
【摘要】 目的 探讨持续性植物状态猫脑脊液中多巴胺的变化及其意义。方法 用高效液相色谱测定持续性植物状态猫脑脊液中多巴胺含量 ,并与正常对照组对比。结果 持续性植物状态猫的脑脊液中多巴胺含量显著降低。结论 多巴胺的减少可能是形成持续性植物状态猫的重要因素之一
【Abstract】 Objective To study the changes of dopamine in cerebrospinal fluid in the cats with persistent vegetative state (PVS). Methods To measure the levels of dopamine in cerebrospinal fluid by high performance liquid chromatography with electrical chemical detect(HPLC ECD) in the cats with PVS and compare the values with the controls. Results The level of dopamine in cerebrospinal fluid in the cats with PVS was obviously lower than that of control groups.Conclusion One of possible pathogenetic causes of PVS in cats is the decrease of dopamine .
【基金】 全军医学科研“十五”计划基金资助项目 (0 1Z0 54);2 0 0 1河南省高校杰出科研人才创新工程基金资助项目(2 0 0 1KYCX0 0 3)
- 【文献出处】 中华神经外科疾病研究杂志 ,Chinese Journal of Neurosurgical Disease Research , 编辑部邮箱 ,2003年02期
- 【分类号】R741
- 【下载频次】62