【摘要】 目的　了解环状电切术 (LEEP)对宫颈疾病 (包括炎症、宫颈癌前病变和早期宫颈癌 )的诊治作用。方法　回顾性分析我院 2 0 0 2年 4月 1日～ 2 0 0 3年 7月 30日因宫颈疾病而行LEEP术的患者共 2 35例。LEEP术由专人进行 ,病理切片由 2位病理科医师检查。结果　本组大部分患者的年龄为 2 0～ 4 9岁 ,以 30～ 39岁者最多 ,占 4 5 .5 % ;术前诊断的宫颈赘生物、宫颈湿疣、宫颈上皮内瘤样病变 (CIN)Ⅰ、CINⅠ～Ⅱ、CINⅡ和CINⅡ～Ⅲ的病例数较术后诊断多 ,但宫颈炎、CINⅢ的病例数术后诊断多于术前诊断 ;且术后诊断发现 9例 (3.8% )宫颈早期浸润癌 ,其中 3例阴道镜下活检为湿疣伴CINⅠ。LEEP术并发症的发生率为 6 .8%。结论　通过三步诊断方法 ,可对宫颈疾病作出明确的诊断 ,以便给予正确的治疗。阴道镜下活检术具有部分的治疗作用 ,但同时存在一定的局限性 ;LEEP技术既可用于全面估计宫颈病变的情况 ,同时也有较确切的治疗效果 ,且不良反应较轻更多还原

【Abstract】 Objective To appraise the value of loop electrical excision procedure in diagnosis and treatment of cervical diseases (cervicitis, cervical intraepithelial neoplasia and cervical cancer). Methods LEEP operation was performed in 235 cases because of cervical diseases in Obstetrics and Gynecology Hospital from Apr.1,2002 to July 30,2003.The procedure was performed by specialized doctors, and the sections were examined by two pathologists. Results Patients’ age ranged from 30～39 years, accounted as 45.5% totolly Cases with cervical hypertrophy, cervical condyloma, CIN Ⅰ、CIN Ⅰ～Ⅱ、CIN Ⅱ and CIN Ⅱ～Ⅲ before LEEP were more in number than those after LEEP, but cervicitis and CIN Ⅲ before LEEP were less than those after LEEP. Nine invasive cervical cancer were diagnosed after LEEP, among them three patients were diagnosed as cervical condyloma and CIN I by colposcopy and biopsy. The complication rate of LEEP was 6.8%. Conclusion Diagnosis cervical diseases can be made through three steps. Colposcopy with biopsy can be beneficial but has some limitations. LEEP technique has become a mainstay in the evaluation and management of cervical diseases with little adverse effect.更多还原