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磁共振动态增强扫描对肾癌诊断价值的探讨

Contrast-enhanced MRI in the diagnosis of renal carcinoma

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【作者】 李传福胡凌马祥兴丛培新王茜张红蕾张晓明

【Author】 LI Chuan-fu,HU Ling,MA Xiang-xing,et al(Imaging Center,Qi lu Hospital of Shandong University)

【机构】 山东大学齐鲁医院影像中心首都医科大学山东大学齐鲁医院影像中心 在读博士

【摘要】 目的:研究动态增强磁共振扫描对肾癌的诊断价值和肾癌的强化特点。方法:对35例肾癌患者行SE序列T1WI,TSE序列T2WI,T1WI,T2WI压脂像,TFE序列动态增强及SE序列延迟T1WI扫描。计算并比较不同序列肿瘤-肾实质对比-噪声比(CNR)。计算增强后肾皮质、髓质、肿瘤的信号强度,并绘出曲线,分析各自不同的强化特点。结果:共检出肾癌35例,直径2~12cm。增强后各个序列图像CNR均较增强前有统计学意义(P<0.05),动态增强序列中肿瘤-肾髓质对比在140s左右最明显。结论:磁共振动态增强扫描是诊断肾癌的有效方法。

【Abstract】 Objective:To evaluate the usefulness of pre-and post contrast-enhanced dynamic MRI in the diagnosis of renal cell carcinomas (RCCs).Methods:Thirty-five patients with thirty-five RCCs and one angiomyolipoma were studied by both conventional spin echo and dynamic contrast-en-hanced MRI.Dynamic MRI was performed with turbo field echo sequence after bolus injection of gadolinium diethylenetriamine pentaacetic acid(Gd-DTPA).Characterization of a renal mass was done by the visual analysis of tumor vascularity as well as quantitative assessment of the contrast noise ratio(CNR)and degree of the enhancement.Results:In the dynamic study the tumor /renal medulla contrast was most conspicuous at140s after initiation of bolus injection of contrast medium.The tumor /renal medulla contrast in the dynamic study was more markedly than that of precontrast T1-weighted imaging and T2-weighted imaging(P<0.05).The tumor /renal medulla contrast in precontrast T1WI SPIR and T2WI SPIR was more striking than in conventional T1-weighted imaging and T2-weighted imaging (P<0.05).Conclusion:Dynamic contrast-enhanced MRI is a useful technique for the diagnosis of RCCs,especially for the patient who is allergic to iodinated contrast material or has renal insufficiency.

  • 【文献出处】 山东大学学报(医学版) ,Acta Academiae Medicinae Shandong , 编辑部邮箱 ,2003年05期
  • 【分类号】R737.11
  • 【被引频次】4
  • 【下载频次】101
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