【摘要】 目的　探讨新生儿败血症的病原及药物敏感情况 ,以指导治疗 ,提高疗效。方法　对我院近 5年来收住的94例血培养阳性 ,确诊为新生儿败血症的病原菌和抗菌药物敏感性进行分析。结果　病原菌以葡萄球菌为主 ,共 69例( 73 40 % ) ,其中表皮葡萄球菌 2 6例 ( 2 7 66% )、溶血性葡萄球菌 14例 ( 14 89% )、金黄色葡萄球菌 12例 ( 12 77% )。其次为大肠埃希菌 10例 (占 10 63% )。青霉素、氨苄青霉素基本耐药 ,含 β 内酰胺酶抑制剂的药物 (氨苄西林舒巴坦、头孢三、四代抗生素 )、亚胺培南、万古霉素、丁胺卡那霉素、环丙沙星敏感率高。结论　根据血培养药敏结果选用敏感抗菌药物 ,可减少细菌耐药性的产生 ,提高临床治疗效果更多还原

【Abstract】 Objective To study the pathogen and drug sensitivity test of neonatal septicemia to direct clinical treatment. Methods The pathogen and the sensitivities of anti-biotic drugs were analysed in 94 cases with positive blood cultures in the past in our hospital 5 years.Results The pathogen was mainly staphylococcus in 69 cases,of which 26 were staphylococcus epidermis(27.66%),14 cases were staphylococcus hemolyticus(14.89%),12 were staphylococcus aureus(12.77%),But 10 cases were Escherichia coli(10.63%).Penicillin and Ampicillin were almost drug-resistant,the sensitivities of those drugs such as β-lactamas drugs(Sulbactam-Ampicillin and Cephalosporin Ⅲ and Ⅳ),vancomycin,kanamycin,ciprofloxacin were higher.Conclusion To choose sensitive antibiotic drugs based on the drug sensitivity tests may decrease the occurrence of drug-resistant bacteria and increase the clinical curative effects.更多还原