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KAIl基因与妇科肿瘤侵袭转移机制关系的研究进展

Progress in study on relationship between KAIl and mechanism of invasive metastasis of gynecologic tumors

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【作者】 符丽华李英勇庞战军

【Author】 FU Li hua 1,LI Ying yong 1,PANG Zhan jun 2 (1.Department of Gynaecology and Obstetrics,The Affiliated Hospital of Guang Dong Medical College,Guangdong Zhanjiang 524023,China;2.Department of Gynaecology and Obstetrics,Nan Fang Hospital,The First Military Medical University,Guangdong Guangzhou 510515,China.)

【机构】 广东医学院附属医院妇产科第一军医大学南方医院妇产科 广东湛江524023广东湛江524023广东广州510515

【摘要】 癌细胞转移是导致癌症患者疗效及预后差的主要原因 ,癌细胞侵袭转移是一个复杂多步骤的过程 ,此过程受多种转移基因和转移抑制基因调控。KAIl是新近发现的基因 ,研究表明KAIl低表达与多种肿瘤的侵袭转移有关。该文就KAIl基因在多种妇科肿瘤研究现状作一综述

【Abstract】 Metastasis of cancer cell is a main cause of poor curative effect and prognosis of patients with cancer. The invasive metastasis of cancer cell is a complex multi step process and is modulated by many kinds of metastasis suppressor genes and metastasis genes. KAIl is a newly found metastasis suppressor gene. Recently, many studies showed that the reduced expression of KAIl was related to invasive metastasis of various kinds of cancers. This paper reviewed the study on KAIl gene in gynecologic tumors.

【关键词】 肿瘤侵袭转移KAIl基因
【Key words】 tumorinvasive metastasisKAIl gene
  • 【文献出处】 国外医学.妇幼保健分册 ,Foreign Medical Sciences Section of Maternal and Child Health , 编辑部邮箱 ,2003年06期
  • 【分类号】R737.3
  • 【下载频次】64
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