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重症SARS的临床治疗及疗效分析

Clinical Analysis and Therapy of Severe Acute Respiratory Syndrome

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【作者】 张复春尹炽标王健陈燕清施海燕洪文昕唐小平

【Author】 ZHANG Fu chun,YIN Chi biao,WANG Jian,CHEN Yan qing, SHI Hai yan,HONG Wen xin,TANG Xiao ping (Guangzhou No.8 Peoples Hospital, Guangzhou 510060, China)

【机构】 广州市第八人民医院感染科广州市第八人民医院感染科 广州510060广州510060广州510060

【摘要】 目的探讨SARS的临床特征及治疗方法。方法对54例重症SARS患者进行回顾性分析。结果54例患者均有高热、进行性呼吸困难和肺部阴影。大多数患者ALT、AST及LDH升高。肺部和免疫系统是病毒主要作用的靶器官。治疗以综合支持对症为主,及时应用无创正压通气和大剂量糖皮质激素治疗有较好疗效。结论综合支持治疗对降低重症SARS的病死率有重要意义。

【Abstract】 Objective To investigate the clinical features and management of critical severe acute respiratory syndrome (SARS ). Methods 54 patients with critical SARS were studied retrospectively. Results All patients manifest high fever and followed by progressive dyspnoea and appearance of lung field shadows in X rays findings. Serum ALT, AST and LDH levels were elevated in most patients. Lungs and immune system were main target organs attacked by the virus. General combination therapy was taken for treating the patients. Continual positive airway pressure (CPAP) and glucocorticoid treatments were effective for control of the disease. Conclusion Comprehensive supportive management is of paramount importance in lowering the mortality of patients with critical SARS.

【基金】 广州市重大科技攻关项目基金(No.2003Z1-E0011)资助。
  • 【文献出处】 热带医学杂志 ,Journal of Tropical Medicine , 编辑部邮箱 ,2003年03期
  • 【分类号】R511.9
  • 【下载频次】38
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