【摘要】 目的　研究妄想性抑郁症的临床特点。方法　按中国精神疾病分类方案与诊断标准第 2版修订本有关标准 ,收集住院的妄想性抑郁症及非妄想性抑郁症病人各 81例 ,方法采用多因素logistic回归分析。结果　妄想性抑郁症与绝望 (相对危险度RR =2 .5 90 )、自责 (RR =2 .80 9)自杀行为 (RR =3 .0 18)、联用抗精神病药 (RR =4.3 85 )及药物显效时间 (RR =1.0 2 7)呈正相关。结论　提示自责、绝望及自杀行为是妄想性抑郁症的危险因素 ,妄想性抑郁症的药物显效时间较迟 ,往往需要联用抗精神病药治疗更多还原

【Abstract】 Objective To explore the clinical characteristics of delusional depression.Methods 81 depressed subjects meeting CCMD-2-R criteria for major depression with delusion were compared with 81 in patients with non-delusion depression, which were analyzed with multinomial logistic model. Results The delusional depression was positively related to hopelessness(RR=2.590),self-blame(RR=2.809),suicidal behavior(RR=3.018) by using antipsychotics(RR=4.385) and presenting the time of marked effect(RR=1.027). Conclusions Hopelessness, self-blame and suicidal behavior were the risking factora of delusional depression, and presenting the time of marked effect for psychotic depression is later and combining treatment is always necessary for the delusional depression.更多还原