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介入化疗栓塞治疗鼻咽癌的临床价值

Clinical Value of Transcatheter Arterial Chemotherapy Embolism in Nasopharyngeal Carcinoma Patients

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【作者】 陈锦生文锡荣郑佳坤詹永忠陈成武许玩兰李奕如陈胜润林介仁张敏

【Author】 CHEN Jin-sheng, WEN Xi-rong, ZHEN Jia-kun, et al. Chaozhou Central Hospital, Chaozhou 521021, China

【机构】 潮州市中心医院潮州市中心医院 广东 潮州 521021广东 潮州 521021广东 潮州 521021

【摘要】 目的:探讨介入动脉化疗栓塞治疗鼻咽癌的临床价值。方法:将87例鼻咽癌患者分成3组:1)A组(介入化疗+放疗组)26例;2)B组(放疗+化疗组)29例;3)C组(单纯放疗组)32例。结果:随访48-61个月,近期疗效CR分别为A组80.8%、B组58.6%、C组50.0%,A组与B、c组分别比较,差异均有显著性(P<0.05);2、3、4年生存率分别为:A组80.8%、76.9%、61.5%,B组58.6%、51.7%、44.8%,C组46.9%、40.6%、37.5%。结论:采用放疗结合介入化疗栓塞对鼻咽癌治疗有协同作用,值得临床推广应用。

【Abstract】 Objective To explore the value of transcatheter arterial chemoembolization (TACE) for nasopharyngeal carcinoma. Methods Eighty-seven cases of nasopharyngeal carcinoma were divided randomized into third groumps:l)A group (transcatheter arterial chemoembolization and radiotherapy), 26 cases.2)B group (radiotherapy and chemotherapy ) ,29 cases.3)C group (simple radiotherapy) ,32 cases. Resi;ts All patients were followed up for 48-61 months.The rates of immediate complete response (CR) of A group,B group and C group were 80.8% and 58.6% and 50.0% respectively (P < 0.05).The A group showed higher 2-,3- and 4-year survival rates than B group and C group with 80.8% ,76.9% ,61.5% and 58.6% , 51.7% ,44.8% and 46.9%,40.6%, 37.5%,respectively (P < 0.01) .Conclusions Radiotherapy plus transcatheter arterial chemotherapy embolism simultaneously for nasopharyngeal carcinoma has synergetic effect, and it needs to be further discussed.

【基金】 广东省卫生系统“五个一工程”重点专科基金资助(96186)
  • 【文献出处】 肿瘤防治杂志 ,Journal of Qilu Oncology , 编辑部邮箱 ,2003年01期
  • 【分类号】R739.63
  • 【下载频次】30
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