节点文献

前列腺癌骨转移疼痛的⁸⁹锶（Sr）治疗

Strontium^-89 for palliation of pain from bone metastases in patients with prostate cancer

推荐 CAJ下载
PDF下载
不支持迅雷等下载工具，请取消加速工具后下载。

【Author】 Ren Xiaomin,Ying Jun,Yao Dehong Department of Urology,Shanghai Ninth People’s Hospital Affiliated to Shanghai Second Medical University (Shanghai 200011) Ye Chuanyang Department of Nuclear Medicine,Shanghai Tumor Hospital Affiliated to Fudan University

【机构】上海第二医科大学附属第九人民医院泌尿外科；复旦大学附属医学院肿瘤医院核医学科上海200011；上海200011；上海200011；

【摘要】目的　探讨前列腺癌骨转移疼痛的89锶 (Sr)治疗。方法　本组 11例明确诊断为前列腺癌 ,并有多个部位骨转移病灶伴有疼痛的病例 ,采用核素89锶静脉内注射治疗。结果　89Sr治疗后 ,疼痛缓解率 3个月为 78.6% ;6个月为 82 .1% ;12个月为 75 .0 %。骨转移病灶数量也明显减少。结论　应用核素89锶治疗中晚期前列腺癌伴骨转移性疼痛是一个比较有效的方法 ,其能够使患者的疼痛获得较为满意的缓解 ,甚至消失 ,从而改善他们的生活质量更多还原

【Abstract】 Objective To investigate the palliative management of pain from bone metastases in prostate cancer with Strontium -89.Methods 11 patients with painful bone metastases of prostate cancer were injected by vein with Strontium -89 choloride ( 89Sr)(dosage 55 μci/kg).Results A significant decrease of bone pain is achieved in 82.1% for 6 months and 75.0% for 12 month.Conclusions 89Sr is an effective agent in palliative therapy for metastatic bone pain in patients with prostate cancer.If required,retreatment can be administered safely.更多还原