【摘要】 目的 :观察卵巢癌实体瘤组织中染色体畸变 ,探索卵巢癌细胞遗传学特异性。方法 :卵巢癌患者肿瘤组织 ,经秋水仙素 3 7℃作用 2 h,两次低渗获得中期分裂相 ,G显带观察。结果 :19例卵巢癌标本中染色体畸变常涉及的染色体有 1,2 ,3 ,5 ,6,7,11,14,17,2 0 ,2 1,X等染色体和多种畸变形式。结论 :小样本卵巢癌实体瘤组织中 ,染色体畸变常发生在一些特定染色体 ,但同时呈较高的不一致性更多还原

【Abstract】 Objective:To investigate peculiar chromosome aberration in ovarian carcinoma.Methods:Mitosis in small pieces of ovarian carcinoma restrained by 0.5μg/ml colchicines (RPMI1640,37℃, 2 hour ) ,metaphase chromosome fixed after hypotonic solution acted on cell twice, chromosome staining by G-banding.Results:Chromosome aberration in 19 patients of ovarian carcinoma arise highly on chromosome 1,2,3,5,6,7,11,14,17,20,21,X. Conclusion:Small number of patients have chromosome aberration on some specific chromosomes but have discordance.更多还原