【摘要】 目的 :观察糖尿病 (DM)性大鼠海绵体的神经病变。　方法 :3 5只SD大鼠随机分为造模组 ( 2 5只 )和空白对照组 ( 10只 )。造模组应用腹腔内单次注射链脲佐菌素 ( 63mg/kg)制造DM模型。单波刺激海绵体神经 ,测定反射潜伏期及肌电位。　结果 :海绵体神经 海绵体平滑肌传导潜伏期中 ,DM组所需时间明显长于其他各组 (P <0 .0 1)。同时 ,与其他各组相比 ,其海绵体平滑肌电位明显升高 (P <0 .0 1)。　结论 :提示DM大鼠海绵体神经病变可能是导致勃起功能障碍的重要原因之一更多还原

【Abstract】 Objectives: To observe the cavernosal nerve dysfunction of diabetic Sprague Dawley rats. Methods: Thirty-five Sprague-Dawley rats were divided randomly into diabetes model group(n=25) and normal group(n=10). Diabetes model was established by administration of streptozotocin (63 mg/kg) in single intraperitoneal dosing. Giving single wave stimulus, corpus cavernosal nerve was measured for its latent period of reaction and myopotential. Results: Compared with other groups, diabetic rats had longer reflection latent period(P< 0.01) and higher corpus cavernosum smooth muscle myopotential (P< 0.01). Conclusions: The results indicate that corpus cavernosal nerve dysfunction may play an important role in the erectile dysfunction of diabetic rats. Natl J Androl,2003,9(3):181-183更多还原