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13C-美沙西汀的含量测定法研究
Quantitative determination of 13C-methacitin stable isotopes in nuclear medicine
【摘要】 目的 研究了诊断用药1 3C -美沙西汀的含量的测定方法 ,建立一种简单的药物含量分析方法 ,指导临床准确用药。方法 先用重氮化滴定法测出1 3C—美西沙汀和主要杂质对 -乙酰胺基酚的总含量 ,再用比色法测出对 -乙酰胺基酚的含量 ,从总量中扣除后者即得1 3C -美西沙汀含量。结果 测得数据与出厂含量基本吻合 ,证明其测定数据准确可靠。结论 该测定方法操作简便 ,是诊断用药1 3C -美沙西汀的含量测定的一种较理想方法。
【Abstract】 Objective The determination method of 13C-methacitin which is diagnose drug was studied to establish a convenient procedune of analysis content of 13C-Methacitin . Methods The method and procedure to determine 13C-Methacitin which is a diagnose drug in 13C breath test was given by titration and spectrophotometry.Results The experiment results showed that the method is accurate and convenient.Conclusion The method is easy to operat. And also it is method of ideal to determination of 13C-Methacitin.
- 【文献出处】 兰州医学院学报 ,Journal of Lanzhou Medical College , 编辑部邮箱 ,2003年03期
- 【分类号】R927.2
- 【下载频次】46