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老年冠心病血清胆红素浓度变化及其与血脂的关系

The change of serum bilirubin and the its relationship with blood lipids in elderly patients with coronary artery disease

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【作者】 张世阳王卫东谈敏

【Author】 ZHANG Shiyang,WANG Weidong,TAN Min.Geriatric Department of Anhui Provincial Hospital,Hefei,230001,China

【机构】 安徽省立医院干部病房安徽省立医院干部病房 230001合肥230001合肥

【摘要】 目的 探讨老年冠心病患者血清胆红素浓度的变化及其与血脂的关系。方法 分别检测 75例老年冠心病患者与 4 5例对照者的血清总胆红素 (TBIL)、直接胆红素 (DBIL)、间接胆红素 (IBIL)浓度以及血清总胆固醇 (TC)、甘油三脂 (TG)、极低密度脂蛋白胆固醇 (VLDL C)水平。结果 冠心病组TBIL、IBIL浓度均低于对照组 ,差异有非常显著意义 (P <0 0 1) ,DBIL浓度也显著低于对照组 (P <0 0 5 )。TBIL、DBIL分别与TG、VLDL C呈显著负相关 (P <0 0 5 )。结论 老年人血清胆红素浓度的降低可能参与了冠心病的发病机制。血清胆红素与血脂负相关

【Abstract】 Objective To explore the change of serum bilirubin and the its relationship with blood lipids in elderly patients with coronary heart disease(CHD).Methods Serum total bilirubin(TBIL),direct bilirubin(DBIL) and indirect bilirubin(IBIL) were measured in 75 patients and 45 normal subjects.The levels of serum total cholesterol(TC),triglycerides(TG) and very low density lipoprotein cholesterol(VLDL C) were also tested.Results The concertration of TBIL and of IBIL were lower in the CHD group than those of control group,the difference was obviously significant(P<0.01).The concertration of DBIL was also significantly lower in the CHD group than that in the control group(P<0.05).TBIL and DBIL were respetively related to negatively the levels of TG and VLDL C(P<0.05).Conclusion The decrease of serum bilirubin in elderly patients might be involved in the pathogenesis of CHD.Serum bilirubin is negatively related with blood lipids.

【关键词】 冠心病胆红素血脂
【Key words】 Coronary heart diseaseBilirubinBlood lipids
  • 【文献出处】 临床中老年保健 ,Journal of Clinical Healthcare , 编辑部邮箱 ,2003年01期
  • 【分类号】R541.4
  • 【下载频次】25
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