【摘要】 目的 :探讨定量检测类风湿因子 (rheumatoidfactor,RF)在类风湿关节炎的诊断、疗效考核方面的应用价值。方法 :速率散射抗原过量比浊法对 5 3例已确诊为类风湿关节炎的病人进行类风湿因子 (RF)定量检测。结果 :有 4 6例 >2 0IU/ml,占 86 .8%。对其中 2 3例经治疗后临床症状有明显缓解者进行RF水平的动态检测 ,其平均值为 38.6IU/ml,并与治疗前结果均值为 6 1.3IU/ml比较 (配对t检验 ,P <0 .0 1)RF水平显著下降。结论 :速率散射抗原过量比浊法定量检测RF对类风湿关节炎的诊断具有重要价值 ,而连续检测RF所呈现的水平变动趋势对该病的疗效考核具有重要意义更多还原

【Abstract】 Objective: To evaluate the value of detection of rheumatoid factor(RF) by rate nephelometry in diagnosis and treatment of rheumatoid arthritis. Method: The levels of serum RF were detected in 53 patients with rheumatoid arthritis.Result: The levels of serum RF in 46 patients were more than 20 IU/ml,the positive rate was 86.8%. Dynamic detection was done in 23 patients who had been treated and relieved, and the levels of serum RF were 38.6 IU/ml,contrasted with 61.3 IU/ml before treated (P<0.01). Conclusion: The detection of serum concentration of RF with rate nephelometry was important to the diagnosis and treatment of rheumatoid arthritis, and the dynamic change of RF could be used to evaluate the curative effect.更多还原