节点文献
前列腺汽化电切术对组织形态及免疫组化的影响
Effect of transurethral electrovaporization of the prostate TUVP on morphology and immunohistochemistry
【摘要】 目的 探讨前列腺汽化电切术标本组织形态学改变及其对免疫表型的影响。方法 采用常规染色和S P法免疫组化染色观察 2 85例前列腺电切标本。结果 (1 )高频电流的高温作用致边缘组织收缩、细胞变形 ,体积变小 ,核染色质浓染 ;腺体变形、靠拢 ,出现假结构和细胞异型。 (2 )前列腺癌特异性的核仁改变不明显。 (3)高频电流的高温使细胞抗原受损 ,前列腺上皮特异性抗原 (PSA)弱表达或不表达。结论 无论是组织学、细胞学还是免疫学 ,前列腺电切标本均与手术切除、穿刺标本均有不同 ,诊断时应考虑上述因素
【Abstract】 Purpose To study the points for attention to the dignosis of the samples of transururethral electrovaporization of the prostate (TUVP) after the heat high frequency electric current,and the changes of the features of immunohistochemistry. Methods To collect the 285 cases of TUVP and observe the changes of their morphology and immunology. Results The periphery of the tissue shrink of circumference, the deformation of cells,the body shorten,chromatin dens;The deformation of glands, chosing and appear are dummy structure and cells atypic. (2)The indistinctiveness of specific change of nucleolie of prostatic carcinoma. (3)The injury of antigen of cells caused by the heat of highfrequency electric current,the faint positive or negative reaction of the prostate specific anting(PSA). Conclusions Sample of transureral electrovaporization of the prostate is different from sample of resection and puncture biopsy in histogy?cytogy and immunohistochemistry. Thus, the above factors should be considered in dignosis.
【Key words】 transurethal disease; electrovaporization of the prostate; morphology; immunohistochemistry;
- 【文献出处】 临床与实验病理学杂志 ,Chinese Journal of Clinical and Experimental Pathology , 编辑部邮箱 ,2003年05期
- 【分类号】R699
- 【被引频次】2
- 【下载频次】25