Relation Between Night Urinary Free Cortisol and Hypertension in Youth

【摘要】 <正> Objectives To study the relation between night urinary free cortisol (UFC) excretion and hypertension in youth. Methods Night urinary free cortisol excretion and blood pressure & its related factor were measured in 188 young people. Results In young men with hypertension the 8 h’s night UFC excretion was significantly higher than that in the group with normal blood pressure 21. 57±6. 28μg/8 h vs 10. 54 ± 5. 46 μg/8 h ( P < 0. 05) . In a group of young people with positive family history of hypertension, the night UFC excretion was much higher than that in the group with negative family history of hypertension. Men excrete much more night UFC than women (12. 73 ± 5. 85 μg/8 h vs 7. 80 ± 4. 15 μg/8 h, P < 0. 05). Conclusions There is an association between hypertension and high 8h’s night UFC excretion; furthermore, there is gender difference in night UFC excretion.更多还原

【Abstract】 Objectives To study the relation between night urinary free cortisol (UFC) excretion and hypertension in youth. Methods Night urinary free cortisol excretion and blood pressure & its related factor were measured in 188 young people. Results In young men with hypertension the 8 h’s night UFC excretion was significantly higher than that in the group with normal blood pressure 21. 57±6. 28μg/8 h vs 10. 54 ± 5. 46 μg/8 h ( P < 0. 05) . In a group of young people with positive family history of hypertension, the night UFC excretion was much higher than that in the group with negative family history of hypertension. Men excrete much more night UFC than women (12. 73 ± 5. 85 μg/8 h vs 7. 80 ± 4. 15 μg/8 h, P < 0. 05). Conclusions There is an association between hypertension and high 8h’s night UFC excretion; furthermore, there is gender difference in night UFC excretion.更多还原