【摘要】 目的　观察支架置入 (SP)术治疗颅外动脉狭窄的疗效及其并发症 ,探讨其安全性与可行性。方法　 2 2例 (平均年龄 6 6岁 )因颅外动脉 (颈内动脉颅外段、椎动脉、锁骨下动脉 )狭窄 >70 %患者行SP术治疗。术前术后行脑血管造影、颈动脉双功能彩超检查。术中术后给予抗凝治疗。术后每 3个月复诊。结果　术后立即行脑血管造影 ,狭窄血管均开通 5 0 %以上。术后 3～ 12个月临床随诊仅 1例出现短暂性脑缺血发作 (TIA) ;颈动脉双功能彩超检查 ,1例出现舒张期短流。本组患者术后 5d内主要并发症有 :1例脑出血合并金黄色葡萄球菌感染死亡 ,1例上消化道出血伴右下肢体无力 ,5例出现TIA。结论　SP为脑血管严重狭窄者提供了新的、有前途的治疗手段 ,但必须严格的掌握适应证与禁忌证。更多还原

【Abstract】 Objective To study the safety and feasibility of stent placement(SP) therapy for extracranial arterial stenosis and to observe its efficacy and complication.Methods Twenty-two patients (mean age 66 years old) were treated with stent placement for >70% stenoses of extracranial arteries(internal carotid arteries,vertebral arteries,subclavian arteries).Cerebrovascular angiography and carotid artery Doppler ultrasound were performed before and after the operation. Anticoagulant was taken during and after the operation. Follow-up was carried out every 3 monthes.Results It was confirmed that all stenosed extracranial arteries were opened >50% measured by cerebrovascular angiography immediately after the operation.During 3-12 months of clinical follow-up after the operation,only 1 case suffered from transient ischemic attack and 1 case suffered from flow break of blood during diastole detected by the Doppler ultrasound.Chief complications in 5 days after the operation were:1 case died of cerebral hemorrhage and Staphylococcus aureus infection, 1case suffered from hemorrhage of upper digestive tract and asthenia of right lower extremity, 5 cases suffered from transient ischemic attack.Conclusions SP provides a new and hopeful therapy for the patients suffering from serious cerebrovascular stenosis. However, the risk is fairly considerable;therefore, indications and contraindications should be considered.更多还原