【摘要】 目的:比较蛛网膜下腔注射吗啡与硬膜外腔注射吗啡用于剖腹产术后镇痛的临床效果及不良反应。方法:30例ASAⅠ～Ⅱ级剖腹产手术病人,随机分为A、B两组,每组15例,均采用蛛网膜下腔阻滞麻醉。腰麻用药为0.5％布比卡因7.5mg。A组于腰麻药液中加入0.2mg吗啡,B组则于硬膜外腔注射2mg吗啡。术后采用视觉模拟法(VAS)行镇痛评分,观察镇痛持续时间及不良反应发生情况。结果:A组术后镇痛持续时间明显长于B组(P<0.05),术后应用哌替啶的人数也明显少于B组(P<0.01),但A组不良反应发生率却显著高于B组(P<0.05)。结论:蛛网膜下腔注射吗啡术后镇痛效果确切、持续时间长,但不良反应发生率却高于硬膜外吗啡组。更多还原

【Abstract】 Objective: To Compare the analgesic effects and side effects of intrathecal morphine with epidural morphine for postcesarean pain relief. Methods: Thirty ASA Ⅰ - Ⅱ Patients undergoing cesarean section were randomly divided into two groups . In intrathecal group (Group A) ,the patients(n = 15) received a subarachnoid injection of 0. 5% bupivacaine 7. 5mg with morphine 0.2mg and in epidural group (Group B), the patients (n= 15) received a intrathecal injection of 0.5% bupivacaine 7.5mg with epidural morphine 2mg. Analgesic effect was assessed by VAS after operation. Analgesic duration and inci-dence of side effects were recorded. Results: Analgesic duration was significantly longer in Group A than in Group B(P<0. 05)and there were markedly fewer patients using Dolantin for postoperative analgesia in Group A than in Group B (P<0.01); But side effects were obviously increased in Group A compared with those in Group B (P<0.05).Conclusion; Intrathecal injection of morphine for postcesarean analgesia is better than epidural morphine but has more side effects.更多还原