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曲马多、多虑平联用治疗丘脑痛的临床研究

Clinical Study on Treatment of Thalamic Pain Using Tramal and Doxepine

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【作者】 邵京山薛敏曹黎波冯玉兰于峻

【Author】 Shao Jingshan Xue Min Cao Libo, et al. (Department of Neurology, Minhang Hospital of Ruijin Hospital Group, SSMU,Shanghai 201100)

【机构】 上海第二医科大学瑞金医院集团闵行医院神经科上海第二医科大学瑞金医院集团闵行医院神经科 上海201100上海201100上海201100

【摘要】 目的 :探讨丘脑痛有效的治疗方法。方法 :随机选择丘脑痛 5 4例 ,分为两组 ,采用曲马多、多虑平联用治疗 2 8例 ;对照组卡马西平治疗 2 6例。以视觉模拟评分法 (visualanaloguescale,VAS)和临床治愈率作为疗效评估指标。结果 :曲马多、多虑平联用治疗组VAS评分 1.36± 0 .37;卡马西平治疗组VAS评分 3.88± 0 .5 3,两组有显著差异 (t=3.973,P <0 .0 0 1)。前者临床治愈 19例 ,治愈率 6 7.86 % ;后者临床治愈 8例 ,治愈率 30 .77% ,两组有显著差异 (χ2 =7.4 18,P =0 .0 0 6 )。结论 :曲马多、多虑平联用治疗丘脑痛的疗效优于卡马西平且不良反应少

【Abstract】 Objective: To investigate the therapeutic effect of thalamic pain. Methods:54 patients with thalamic pain were randomly divided into two group: 28 cases received the combined treatment with tramal and doxepine; 26 cases of controls by carbamazepine. Results:The results showed that visual analogue scale of treated group as 1.36±0.37 while the control group was 3.88±0.53. There was statistical significant difference in VAS between the two group (t=3.973 ,P<0.001 ). The clinical cure rate of treated group as 67.86 % while the control group was 30.77%. There was statistical significant difference in The clinical cure rate between the two group (χ 2=7.418, P=0.006). Conclusion:It suggests that the curative effect of combined treatment with tramal and doxepine is better than that of carbamazepine.

  • 【文献出处】 中国临床医学 ,Clinical Medical Journal of China , 编辑部邮箱 ,2003年02期
  • 【分类号】R741
  • 【被引频次】9
  • 【下载频次】189
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