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系统性红斑狼疮患者136例疾病活动性的评价
Evaluation of disease activity in 136 inpatients with systemic lupus erythematosus
【摘要】 目的:探讨系统性红斑狼疮(SLE)患者疾病活动指数(SLEDAI)的价值。方法:以SLEDAI作为评价SLE患者疾病活动性的标准。结果:136例SLE患者SLEDAI得分最小为0分,最大为52分,平均(12.88±10.58)分,男女相比差异无显著性(P>0.05)。抗核抗体(ANA)、抗Sm抗体与SLEDAI无相关性。农村患者与城市患者SLEDAI相比,差异有显著性(P<0.05)。SLEDAI与患者住院天数相关(相关系数r=0.477,P<0.05)。结论:SLEDAI为一种较好的评价SLE患者疾病活动性的方法,是患者治疗、预后评价的有用指标。
【Abstract】 Objective:To study the value of SLEDAI (systemic lupus erythematosus disease activity index)in evaluating the activities of SLE inpatients.Methods:SLEDAI was used to measure the disease activity in136SLE in patients.Results:The scores range from0to52,with mean value of 12.88±10.58.No statistical difference is detected between men and wom en(P>0.05).There is no correlation between ANA?anti-Sm anti body and SLEDAI.But the significant difference is ob-served between the patients who live in country and city(P<0.05).SLEDAI is correlated with inpatients’hospitalization days(r=0.477,P<0.05).Conclusions:SLEDAI is a valuable method in measure ment of SLE disease activity,which also in forms an effective in strument in treatment and prognosis for SLE patients.
【Key words】 lupus erythematosus,systemic; disease activity in dex; measurement J Clin Dermatol,2003,32(8)-448;
- 【文献出处】 临床皮肤科杂志 ,Journal of Clinical Dermatology , 编辑部邮箱 ,2003年08期
- 【分类号】R593.241
- 【被引频次】3
- 【下载频次】72