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131I-MIBG肾上腺髓质扫描对嗜铬细胞瘤的诊断价值
Value of Iodine-131 MIBG for the diagnosis of pheochromocytoma
【摘要】 目的 :评价13 1I MIBG肾上腺髓质扫描在嗜铬细胞瘤的诊断价值。方法 :16例患者术前均经B超检查及13 1I MIBG肾上腺髓质扫描 ,10例术前行CT检查。结果 :14例患者经13 1I MIBG肾上腺髓质扫描直接提示病灶部位核素浓聚 ,其中包括 6例血压正常或临界正常患者。B超检查提示嗜铬细胞瘤不能排除诊断 5例 ,CT检查提示嗜铬细胞瘤可能 4例。本组13 1I MIBG肾上腺髓质扫描敏感性 87.5 % ,特异性 10 0 %。结论 :13 1I MIBG肾上腺髓质扫描对嗜铬细胞瘤的诊断价值在于其可直接反映可疑肿瘤的嗜铬性质 ,具有高效、可靠的优点 ,应作为嗜铬细胞瘤的首选功能性诊断手段
【Abstract】 Purpose:To evaluate the role of 131 I MIBG in the diagnosis of pheochromocytoma. Methods:The records of 16 inpatients with pheochromocytoma since 1996 were identified. Fourteen were adrenal pheochromocytoma, 2 were abdominal paraganglioms. Ten patients had symptoms such as hypertension, amaurosis, 6 patients had normal or critical blood pressure. Results:Fourteen of sixteen cases were distinguished accurately by Iodine 131 MIBG scintigraphy,including 6 no hypertension cases. All the positive cases were confirmed by post operative biopsy. The specificity of Iodine 131 MIBG scintigraphy was 100%, and sensitivity was 87.5 %. Conclusions:The outstanding accuracy of Iodine 131 MIBG scintigraphy questions the diagnosis of pheochromocytoma preoperatively. And it targets the metabolic information of pheochromocytoma. The marvelous specificity leads to pheochromocytoma diagnosis with every positive case. It should be used as the first choice for the suspected masses.
【Key words】 Pheochromocytoma; Adrenal gland neoplasms; Radionuclide imaging;
- 【文献出处】 临床泌尿外科杂志 ,Journal of Clinical Urology , 编辑部邮箱 ,2003年08期
- 【分类号】R736
- 【被引频次】18
- 【下载频次】84