【摘要】 目的　探讨长管状骨嗜酸性肉芽肿的临床特征。方法　总结 11例长管状骨嗜酸性肉芽肿患者病史资料 (2例为多发性 ) ,病程 2周～ 2年 ,除 1例多发性患者活检术后行小剂量激素和放疗外 ,其余 10例均行病灶清除 +植骨或肌瓣填塞术。分析病程中所共有的临床特征。结果　诊断均经术后病理检查证实。病灶均发生于下肢骨 ,无诱因性患肢痛伴跛行为主要症状 ,无典型发热史 ,患肢无典型体征。X线片依病程长短具有一定的特征性表现。平均随访 2 6个月 ,未见复发及新的病灶。结论　长管状骨的嗜酸性肉芽肿多孤立性地发生于骨干 ,缺乏典型的临床症状和体征 ,X线片具有一定特征性 ,预后良好。更多还原

【Abstract】 Objective To study the clinical featur es of solitary eosinophilic granuloma of long tube bone in children. Methods 11 cases (2 cases of multiple lesions) with solitary eosinophilic granuloma of long tube bone were analyzed retrospectively. The course of disease was 2 weeks～2 years. 1 case of multiple lesions had been treated with a small volume of steroid drug and radiotherapy after the biopsy , the rest 10 cases had been through a curettage of the bone lesion with bone graft or muscle packing. The general clinical features of these patients were concluded. Results The diagnosis had been proved by the post operative histopathology. The lesions occurred in lower limbs. No causing pain of the involve limb with lame was the main complaint.No typical fever and special signs for differential diagnosis was found.The plain radiograph gave typical shows depending on the phase of the disease. The mean follow up time was 26 months (15～30 months). All cases were found without signs of recurrence or new lesions through follow up. Conclusion The eosinophilic granuloma is usually solitarily occurred on the diaphysis of long tube bone,which is short of special clinical signs. The plain radiography shows a relative features, and it has a good prognosis.更多还原