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肺癌患者血清中微量元素的检测及其临床价值

Determination of serum trace elements and their clinical value in patients with lung cancer

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【作者】 王子玲张伟张虹妍刘新张霞

【Author】 WANG Zi ling, ZHANG Wei, ZHANG Hong yan, et al. Sixth Department of Internal Medicine, Chest Hospital of Henan Province, Zhengzhou 450003,China

【机构】 河南省胸科医院内六科河南省胸科医院内六科 河南郑州450003河南郑州450003河南郑州450003

【摘要】 目的 检测肺癌患者血清中微量元素的水平 ,并探讨对肺癌辅助诊断的临床价值。方法 采用原子吸收分光光度法及 72 1分光光度法同时测定血清样品中铜、锌、铁、镁及钙等 5种微量元素的含量。结果 肺癌组及肺良性疾病组患者血清铜含量和铜 锌比值均高于正常对照组 ,而锌、钙、镁含量均低于正常对照组 ,差异有非常显著性意义 (P <0 .0 1) ,而且肺癌组与肺良性疾病组血清铜、铁、钙及铜 锌比值相比差异也有显著性意义 (P <0 .0 5 )。结论 测定肺癌患者血清中铜 锌比值和钙、镁含量对肺癌的辅助诊断有一定的参考价值

【Abstract】 Objective To determine the levels of serum trace elements in patients with lung cancer, and study the clinic value in the assistant diagnosis. Methods The levels of Cu,Zn,Fe,Mg and Ca were detected by atomic absorption spectrophotometer and 721 spectrophotometer. Results The level of Cu and ratio of Cu/Zn in patients with lung cancer and with benign disease are significantly higher than that in controls, but the levels of Zn,Ca,Mg are obviously lower (P< 0.01 ). The levels of Cu,Fe,Ca,and Cu/Zn in patients with lung cancer are different from those in benign disease. Conclusion Determination of serum Cu/Zn,Ca and Mg in patients with lung cancer hasa referential value for assistant diagnosis in clinic. KER WORDS: lung neoplasms; trace elements; spectrophotometry,atomic absorption;spectrophotometry

  • 【分类号】R734.2
  • 【被引频次】12
  • 【下载频次】88
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